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Filtered Search Results
Ambeed tertButyl propiolate
tert-Butyl propiolate, 13831-03-3, 95%
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Medchemexpress LLC Lisuride maleate | 19875-60-6 | 99.97% | 454.52 | 50 MG
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Lisuride (maleate) is a potent dopamine agonist that is believed to act directly on dopaminergic receptors. It is an ergot derivative. This compound has been shown to alleviate premenstrual mastalgia without significant side effects. Lisuride (maleate) has been studied in vivo, demonstrating 3-4 times higher potency when administered intraperitoneally (i.p.) compared to orally (p.o.). It effectively antagonizes motor depression and hypothermia induced by reserpine. At dosages as low as 0.10 mg/kg i.p., it is comparable in effectiveness to apomorphine and D-amphetamine in causing significant hypothermia. The product is for research use only and not sold to patients.
- Potent dopamine agonist
- Ergot derivative
- Therapeutic potential for premenstrual mastalgia
- Suitable for research applications
- High purity
- Versatile formulations
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Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.84% | 391.42 | 1 ML
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Omigapil maleate (CGP3466B) is an orally active GAPDH nitrosylation inhibitor. It has been shown to abrogate Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. This compound holds potential for research in Alzheimer's disease and congenital muscular dystrophy (CMD), and it also acts as an apoptosis inhibitor. Additionally, Omigapil maleate is a click chemistry reagent, possessing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Orally active GAPDH nitrosylation inhibitor
- Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction abrogator
- Potential for Alzheimer's disease research
- Apoptosis inhibitor
- Can be used for congenital muscular dystrophy (CMD) research
- Click chemistry reagent with an Alkyne group for CuAAc reactions
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eMolecules 2,2,6,6-Tetramethyl-4-piperidyl methacrylate | 31582-45-3 | MFCD06200811 | 1g
Combi-Blocks | 2,2,6,6-Tetramethyl-4-piperidyl methacrylate | 1g | 342862384 | QC-3538 | 95.000 | 31582-45-3 | MFCD06200811 | 225.332 | C13H23NO2
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Selleck Chemical LLC Indacaterol Maleate S3083-5mg
Indacaterol (QAB149) is an ultra-long-acting -adrenoceptor agonist with pKi of 7 36 for 1-adrenoceptor and pKi of 5 48 for 2-adrenoceptor
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Medchemexpress LLC Cediranib maleate | 857036-77-2 | MFCD09954115 | 100.0% | C29H31FN4O7 | 10MG
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Cediranib maleate is the maleate salt of cediranib (AZD-2171), a potent orally available vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor supplied for research use. It is provided as a high-purity solid and is also available in ready-to-use DMSO stock solutions for biochemical and cell-based assays.
- High purity 99.95%.
- Potent VEGFR inhibitor with low-nanomolar activity against Flt1, KDR, Flt4, PDGFRα/β, and c-Kit.
- Suitable for in vitro and in vivo research applications.
- Supplied as a solid and as 10 mM DMSO solutions.
- Molecular formula C29H31FN4O7; molecular weight 566.58 Da.
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Sigma Aldrich Fine Chemicals Biosciences Ethyl-trans-2-octenoate >=98%, FG | 7367-82-0 | MFCD00015287 | 100G
Ethyl-trans-2-octenoate >=98%, FG | Purity: >=98% | Mol Wt: 170.25 | 7367-82-0 | MFCD00015287 | 100G
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Medchemexpress LLC Pimethixene maleate | 13187-06-9 | 99.7% | 5 MG
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Pimethixene maleate is an antihistamine and antiserotonergic compound that acts as an antimigraine agent. It is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4, as well as muscarinic M1 and M2 receptors. The pKis for these receptors are 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61, and 9.38, respectively.
- Antihistamine and antiserotonergic compound.
- Acts as an antimigraine agent.
- Highly potent antagonist of multiple receptors including 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4, and muscarinic M1 and M2.
- For research use only.
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Medchemexpress LLC Pirepemat fumarate (IRL752 fumarate) | 2251806-70-7 | >98.26% | 329.30 | 100 MG
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Pirepemat fumarate (IRL752 fumarate) is a cortical-preferring catecholamine- and cognition-promoting agent. It is utilized for the study of Parkinson's disease.
- Cortical-preferring catecholamine agent
- Cognition-promoting agent
- Used for the study of Parkinson's disease
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Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 25 MG
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Tegaserod maleate is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. It induces tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling, and decreases S6 phosphorylation, exhibiting anti-tumor activity.
- Orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist
- 5-HT2B receptor antagonist
- Induces tumor cell apoptosis
- Blunts PI3K/Akt/mTOR signaling
- Decreases S6 phosphorylation
- Exhibits anti-tumor activity
- Potential for irritable bowel syndrome (IBS) research
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Medchemexpress LLC Indacaterol maleate | 753498-25-8 | C28H32N2O7 | 500 MG
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Indacaterol maleate is an orally active, ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. It inhibits NF-κB activity in a β-arrestin2-dependent manner, which helps prevent further lung damage and improves lung function in chronic obstructive pulmonary disorder (COPD). It can also be utilized in cardiovascular disease research.
- Orally active, ultra-long-acting β2 adrenergic receptor (ADRB2) agonist.
- Inhibits NF-κB activity in a β-arrestin2-dependent manner.
- Helps prevent further lung damage.
- Improves lung function in chronic obstructive pulmonary disorder (COPD).
- Can be used in cardiovascular disease research.
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Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 1 ML
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Tegaserod maleate is an orally active serotonin receptor 4 (HTR4) agonist and a 5-HT2B receptor antagonist. It demonstrates anti-tumor activity by inducing tumor cell apoptosis and blunting PI3K/Akt/mTOR signaling. It is also being researched for its potential in treating irritable bowel syndrome (IBS) and diabetic gastropathy.
- Potent agonist of 5-HT4 receptor
- Antagonist of 5-HT2B receptor
- Induces tumor cell apoptosis
- Blunts PI3K/Akt/mTOR signaling
- Decreases S6 phosphorylation
- Accelerates gastric emptying rate
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Medchemexpress LLC Dibutyl maleate | 105-76-0 | MFCD00008544 | 99.19% | 228.28 | 1 ML
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Dibutyl maleate is the diester of Maleic Acid. It can be used as an intermediate of pharmaceutical synthesis and is known to enhance contact sensitization to Fluorescein isothiocyanate in mice.
- Used as an intermediate of pharmaceutical synthesis.
- Enhances contact sensitization to fluorescein isothiocyanate in mice.
- Molecular weight: 228.28.
- Chemical formula: C12H20O4.
- CAS number: 105-76-0.
- Purity: 99.19%.
- Appears as a colorless to light yellow liquid.
- Soluble in DMSO (100 mg/mL).
- Storage conditions vary based on form (pure or in solvent).
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Apexbio Technology LLC (S)-(+)-Dimethindene maleate(Synonyms: (+)-Dimethindene maleate, Dexdimethindene maleate, (S)-Dimetindene maleate, (S)-(+)-Dimetindene maleate), 50mg, CAS: 136152-65-3.
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(S)-( )-Dimethindene maleate (CAS 136152-65-3) is a small molecule antagonist exhibiting selective affinity for the muscarinic acetylcholine receptor subtype M2 while showing comparatively reduced interaction with M1 M3 and M4 subtypes Additionally it acts as an antagonist at histamine H1 receptors Due to its receptor selectivity profiles it is employed in pharmacological studies investigating autonomic regulation mechanisms cardiovascular physiology and respiratory system function
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Apexbio Technology LLC (+)-MK 801 Maleate 77086-22-7 10mg
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( )-MK 801 Maleate is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor exhibiting a Ki value of approximately 30 5 nM By blocking the NMDA receptor-mediated ion channel MK 801 disrupts glutamate-associated excitatory neurotransmission In experimental models MK 801 demonstrates anticonvulsant and anxiolytic properties through modulation of NMDA receptor activity This compound readily penetrates the central nervous system binding reversibly and region-specifically to cortical and hippocampal membranes MK 801 effectively inhibits NMDA-triggered depolarization responses in neuronal preparations making it applicable in studies focused on epilepsy excitotoxicity and neuronal signaling pathways
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